【英语单词】彻底解释“hybridized”! 含义、用法、例句、如何记忆

【英语单词】彻底解释“hybridized”! 含义、用法、例句、如何记忆

「hybridized」の意味(adjective)

词性(英语单词分类):形容词
通常 在英国 交配
生物学 专门

用于表示[由两种不同类型的植物或动物组成]。

中文翻译:【杂交】

例文
Genetically speaking, thesehybridised creatures would not quite be full clones.
从遗传学上来说,这些杂交生物并不是完美的克隆。
例文
Many people are allergic to hybridized peanuts.
许多人对杂交花生过敏。

它用来表示[由两种不同的事物组成并具有两者的特征]。

例文
Industrial nations now have hybridized styles of government which are part capitalist, part socialist, and part mercantile (run by big business).
工业化国家现在有一种混合型政府,一半是资本主义,一半是社会主义,一半是商业化(由大公司运营)。
例文
The artist is interested in the hybridised culture of contemporary society.
艺术家对现代社会的混合文化感兴趣。
【英语单词】彻底解释“hybridized”! 含义、用法、例句、如何记忆

“hybridized”的同义词列表。 让我们按顺序来记住吧!。

  • blended
  • different
  • diverse
  • varied
  • alloyed
  • amalgamated
  • assimilated
  • assorted
  • brewed
  • compound
  • conglomerate
  • crossbred
  • crossed
  • disordered
  • diversified
  • embodied
  • fused
  • incorporated
  • infused
  • interbred
  • joint
  • married
  • merged
  • mingled
  • motley
  • tied
  • united
  • woven
  • composite
  • heterogeneous
  • hybrid
  • interdenominational
  • miscellaneous
  • mongrel
  • multifarious

通过记住反义词和反义词列表来掌握“hybridized”这个词!。

  • alike
  • like
  • same
  • similar
  • uniform
  • separate
  • single
  • lone
  • singular
  • uncombined

“hybridized”是一个英语单词,有几个不同的含义。 让我们用例句来解释每个的含义和用法!

英语 含义(中文翻译) 详细解释!
hybridize [sth] ,
also UK: hybridise [sth]
(产生杂交品种)
hybridize,
also UK: hybridise
杂交 (杂交)

hybridized是一个英语单词,有几个不同的含义。 让我们用例句来解释每个的含义和用法!

Western music has happily hybridized with other sounds, transforming itself.
西方音乐愉快地与其他声音 混合 和转变。
Via E 200 petrol, and hybridized by a 82 hp electric motor and technology Plug-in, the E350 and configures the hybrid option saloon, with a global power 258 hp and 600 Nm of torque. announces 30 km of electric range and an average consumption of 2.1 l/ 100 km, equivalent to 49 g/ km.
E 200通过汽油和82马力 电动机 混合动力和技术插电式混合动力,设置了E350混合动力轿车,全球功率258马力和600牛米扭矩。宣布30公里e在炉子上,平均油耗为2.1升/100公斤,相当于49克/公斤。
The hybridized DNA chips are scanned and the density data in each probe region are obtained as gene expression data (Step P5).
用扫描仪对 杂交的 DNA芯片进行成像,获得每个探针区域的浓度数据作为基因表达数据(步骤P5)。
This naphthoquinone compound is located at such a position as facing to the cytosine to be determined when the photofunctional nucleic acid is hybridized with the DNA having the base sequence of the p53 gene.
这里,萘醌化合物设置在当光功能核酸与具有p53基因的碱基序列的DNA 杂交 时面对待测定的胞嘧啶的位置处。
Cyclopropane is analogous to a triangle and thus has bond angles of 60º, much lower than the preferred 109.5º of an sp3 hybridized carbon.
环丙烷类似于三角形,因此键角为 60°,远小于 sp3 化碳原子所需的 109.5°。
Even though they are often referred to as “nature documentaries,” these films are just as are hybridized and committed as Jarl’s grittier Mods series.
虽然它经常被称为自然纪录片,但它的 混合性 和参与度并不亚于 Jarl 大胆的 Mod 系列。
It is possible to efficiently obtain a fluorine-containing olefin in which the fluorine atoms bonded to the sp2 hybridized carbon atoms of a fluorine-containing olefin, such as TFE, have been substituted with organic groups by reacting a fluorine-containing olefin and an organic magnesium compound in the presence of a catalyst containing nickel or palladium.
在本发明中,通过使含氟烯烃与有机镁化合物在含有镍或钯的催化剂存在下反应,将与TFE等含氟烯烃的sp2 化碳原子键合的氟原子置换为可以有效地得到含氟烯烃。
The probe nucleic acids are fixed to the same positions as the primer immobilization regions or to probe immobilization regions in proximity thereto, and hybridized signals are independently detected.
将探针核酸固定在探针固定区域上与引物固定区域相同的位置或其附近,并独立地检测 杂交 信号。
The photofunctional nucleic acid is hybridized with the DNA having the base sequence of the p53 gene and then photo, the DNA is cleaved exclusively in the case where the cytosine facing to the naphthoquinone compound has been methylated.
通过 将该 光功能性核酸与具有p53基因的碱基序列的DNA杂交并用光照射,仅当面对萘醌化合物的胞嘧啶被甲基化时,该DNA才被切割。
At P = 1.4 GPa (f) the hybridized mode of transverse and longitudinal fluctuations (h-TL) does exist in addition to Nambu-Goldstone (NG) and Higgs-amplitude (L) modes.
在 P = 1.4 GPa 的压力诱导有序相 (f) 中,除了 Southern-Goldstone (NG) 模式和 Higgs (L) 模式外,还发现了纵向和横向波动的 混合 模式 (h-TL)存在、认识。
A target nucleic acid can be detected conveniently and with high sensitivity by using transglutaminase (TGase) and also by using a multilabeled nucleic acid probe having multiple labeling parts introduced therein covalently in advance or covalently introducing multiple labeling parts into a nucleic acid probe that has been hybridized with the target nucleic acid.
通过使用预先使用转谷氨酰胺酶(TGase)共价引入多个标记部分的多标记核酸探针,或者通过共价 标记 与目标核酸杂交的核酸探针。酸的检测很容易且灵敏度高。
Use is made of: (a) polynucleotide having a base sequence of SEQ ID No. 1, or (b) polynucleotide coding for a protein having D-lactic acid dehydrogenase activity, having been hybridized under stringent conditions with a probe prepared from the whole or part of a base sequence of SEQ ID No. 1 or complementary strand thereof.
(a)具有SEQ ID NO:1所示的核苷酸序列的多核苷酸;(b)与由SEQ ID NO:1所示的整个核苷酸序列或其一部分或其互补链制备的探针杂交的多核苷酸在 严格 条件下,并利用编码具有D-乳酸脱氢酶活性的蛋白质的多核苷酸。
This semiconductor element is characterized by comprising an electric current path (16) formed of a plurality of carbon nanotubes (18) and two or more electrodes (14, 15) connected to the electric current path, at least one or more of the electrodes being formed of a mixture of a metal with a carbon material (17) having an SP2 hybridized orbital such as a multiwall carbon nanotube, a glassy carbon, or graphite particles.
一种半导体装置,具有由多个碳纳米管(18)构成的电流路径(16),具有与该电流路径连接的两个以上的电极(14、15),并且具有至少一个电极。电极由金属和多壁碳纳米管、玻璃碳或石墨颗粒等具有SP2 杂化 轨道的碳材料(17)的混合物构成。
In the disordered phase at low pressures single mode of singlet – doublet excitation is observed.In contrast in the pressured induced ordered phase at 1.4 GPa, it was discovered that the hybridized mode of longitudinal and transverse fluctuations originated from noncollinearity of the magnetic structure as well as Nambu-Goldstone and Higgs-amplitude modes.
在低压自旋无序状态下,观察到单重态-双重态激发,而在1.4 GPa的有序相中,除了南部-戈德斯通模式和希格斯模式外,还观察到磁性结构的非磁性结构。结果表明,存在由共线性引起的纵向和横向 波动 的混合模式。
Jovial Foods sent me a box of their Organic Einkorn Wheat Berries to try.According to Jovial Foods, einkorn is “the world’s most ancient wheat and the only wheat that has never been hybridized .”
Yoki Foods 寄给我一盒他们的有机细菌浆果让我尝尝。Merry Foods 的细菌是唯一从未与世界上最古老的小麦 杂交 过的小麦。
A method of detecting a methylated cytosine of the invention comprises the steps of: hybridizing an oligonucleotide capable of hybridizing to a region containing a cytosine which is expected to be methylated in a sample DNA and having an abasic site at a position complementary to the cytosine to the sample DNA; oxidizing a methylated cytosine by reacting an oxidizing agent with the hybridized sample DNA formed in the previous step when a methylated cytosine is present therein; and detecting the oxidized methylated cytosine.
本发明的甲基化胞嘧啶的检测方法包括将与样品DNA中含有预期被甲基化的胞嘧啶的区域杂交并且在与胞嘧啶互补的位置处具有脱碱基位点的寡核苷酸与样品DNA组合。当存在甲基化胞嘧啶时,使该步骤中产生的 杂交 样品DNA与氧化剂反应,氧化甲基化胞嘧啶;该方法包括检测结合胞嘧啶的步骤。
The method for synthesizing a nucleic acid in which a complex of a target nucleic acid to which a primer oligonucleotide is hybridized and DNA polymerase β is formed, a fluorescently labeled dNTP is allowed to be incorporated into the DNA polymerase β, the fluorescently labeled dNTP is bound to the 3′ end of the primer oligonucleotide and the fluorescently labeled dNTP is allowed to be incorporated into the DNA polymerase β continuously, whereby a nucleic acid complementary to the target nucleic acid is extended from the 3′ end of the bound fluorescently labeled dNTP.
与引物寡核苷酸 杂交的 靶核酸与DNA聚合酶β之间形成复合物,荧光标记的dNTP掺入DNA聚合酶β中,并且荧光标记的dNTP与引物寡核苷酸的3’端结合。一种核酸合成方法,其中通过将荧光标记的dNTP连续地掺入DNA聚合酶β中,使与目标核酸互补的核酸从结合的荧光标记的dNTP的3’末端延伸。
The following are provided: a nucleic acid containing a base sequence represented by one of sequence numbers 1 to 1281; a nucleic acid at least 90% identical to the aforementioned nucleic acid; a nucleic acid hybridized with a complementary strand of the aforementioned nucleic acid under stringent conditions; a nucleic acid containing the second through eighth base sequences of a base sequence represented by one of sequence numbers 1 to 594; a cell or organ fibrosis control agent using a nucleic acid or the like comprising a base sequence that is complementary to the base sequence of an abovementioned nucleic acid; a diagnostic or therapeutic agent for disorders resulting from cell or organ fibrosis; an expression control agent for target genes of nucleic acids such as microRNAs; a control method or the like for cells and organs; and a method for screening for cell or organ fibrosis control agents.
本发明涉及包含SEQ ID NO:1至1281中任一个所表示的碱基序列的核酸、与该核酸具有90%以上同一性的核酸、以及在严格条件下与互补序列 杂交的 核酸。 、细胞或器官纤维化控制剂、细胞或器官纤维化引起的疾病的诊断或治疗剂、微小RNA等核酸靶基因的表达控制剂、细胞和器官控制方法等。提供了用于筛选纤维化控制剂的方法。
A method comprising: the double-stranded nucleic acid step wherein a nucleic acid probe immobilized on an electrode is hybridized with a gene sample to form a double-stranded nucleic acid; the step of adding an insertion agent comprising a compound having a double-stranded nucleic acid-binding site Ia, which is to be inserted specifically into the above-described double-stranded nucleic acid and forms a covalent bond with the double-stranded nucleic acid upon light irradiation, an electrochemically active site Fahaving an electrochemical activity, and a linking site La of linking the double-stranded nucleic acid-binding site Ia to the electrochemically active site Fa, and having substituent(s) comprising one or both of compounds represented by -Lb-Ib and -Lc-Fb at each of the sites as described above; the light irradiation step of forming a covalent bond between the double-stranded nucleic acid and the inserting agent; and the detection step of detecting the inserting agent forming a covalent bond with the double-stranded nucleic acid by an electrochemical measurement.
双链核酸步骤,其中固定在电极上的核酸探针与基因样品 杂交 以形成双链核酸;双链核酸结合位点Ia与双链形成共价键。添加由具有位点La的化合物组成的嵌入剂的步骤[0072] 在各位点具有由-Lb-Ib和-Lc-Fb表示的化合物中的一种或其组合构成的取代基。 光照射步骤,用于使双链核酸与嵌入剂共价键合;以及检测步骤,通过电化学测量来检测与双链核酸共价键合的嵌入剂。
Disclosed is an L-succinyl aminoacylase comprising (a) a protein coded by a gene consisting of the base sequence disclosed in sequence no. 1; (b) a protein consisting of the amino acid sequence disclosed in sequence no. 2; (c) a protein coded by a polynucleotide hybridized with a base sequence complementary to the base sequence disclosed in sequence no. 1 under stringent conditions, and which possesses L-succinyl aminoacylase activity; or (d) an amino acid sequence, in which one or multiple amino acids are substituted, deleted, inserted, and/or added to a protein consisting of the amino acid sequence disclosed in sequence no. 2, and which possesses L-succinyl aminoacylase activity.
根据本发明,(a)由由SEQ ID NO:1所示的核苷酸序列组成的基因编码的蛋白质;(b)由SEQ ID NO:2所示的氨基酸序列组成的蛋白质;( c)由由SEQ ID NO:1所示的核苷酸序列组成的基因编码的蛋白质;由在严格条件下与与该核苷酸序列互补的核苷酸序列 杂交 并具有L-琥珀酰氨基酰化酶活性的多核苷酸编码的蛋白质;或(d)由SEQ ID NO:2所示的氨基酸序列组成。 提供一种由其中一个或多个氨基酸被取代、缺失、插入和/或添加的氨基酸序列组成的L-琥珀酰酰基转移酶,且其具有L-琥珀酰氨基酰化酶活性。

听“ hybridized ”的陆地声音(发音)!

读法是【ˈhaɪ.brɪ.daɪzd】。 听下面的视频并大声发音【ˈhaɪ.brɪ.daɪzd】。

【必听】美国人解释“hybridized”的含义

「hybridized」の意味(adjective)

词性(英语单词分类):形容词
通常 在英国 交配
生物学 专门

用于表示[由两种不同类型的植物或动物组成]。

中文翻译:【杂交】

例文
Genetically speaking, thesehybridised creatures would not quite be full clones.
从遗传学上来说,这些杂交生物并不是完美的克隆。
例文
Many people are allergic to hybridized peanuts.
许多人对杂交花生过敏。

它用来表示[由两种不同的事物组成并具有两者的特征]。

例文
Industrial nations now have hybridized styles of government which are part capitalist, part socialist, and part mercantile (run by big business).
工业化国家现在有一种混合型政府,一半是资本主义,一半是社会主义,一半是商业化(由大公司运营)。
例文
The artist is interested in the hybridised culture of contemporary society.
艺术家对现代社会的混合文化感兴趣。
【英语单词】彻底解释“hybridized”! 含义、用法、例句、如何记忆

“hybridized”的同义词列表。 让我们按顺序来记住吧!。

  • blended
  • different
  • diverse
  • varied
  • alloyed
  • amalgamated
  • assimilated
  • assorted
  • brewed
  • compound
  • conglomerate
  • crossbred
  • crossed
  • disordered
  • diversified
  • embodied
  • fused
  • incorporated
  • infused
  • interbred
  • joint
  • married
  • merged
  • mingled
  • motley
  • tied
  • united
  • woven
  • composite
  • heterogeneous
  • hybrid
  • interdenominational
  • miscellaneous
  • mongrel
  • multifarious

通过记住反义词和反义词列表来掌握“hybridized”这个词!。

  • alike
  • like
  • same
  • similar
  • uniform
  • separate
  • single
  • lone
  • singular
  • uncombined

“hybridized”是一个英语单词,有几个不同的含义。 让我们用例句来解释每个的含义和用法!

英语 含义(中文翻译) 详细解释!
hybridize [sth] ,
also UK: hybridise [sth]
(产生杂交品种)
hybridize,
also UK: hybridise
杂交 (杂交)

hybridized是一个英语单词,有几个不同的含义。 让我们用例句来解释每个的含义和用法!

Western music has happily hybridized with other sounds, transforming itself.
西方音乐愉快地与其他声音 混合 和转变。
Via E 200 petrol, and hybridized by a 82 hp electric motor and technology Plug-in, the E350 and configures the hybrid option saloon, with a global power 258 hp and 600 Nm of torque. announces 30 km of electric range and an average consumption of 2.1 l/ 100 km, equivalent to 49 g/ km.
E 200通过汽油和82马力 电动机 混合动力和技术插电式混合动力,设置了E350混合动力轿车,全球功率258马力和600牛米扭矩。宣布30公里e在炉子上,平均油耗为2.1升/100公斤,相当于49克/公斤。
The hybridized DNA chips are scanned and the density data in each probe region are obtained as gene expression data (Step P5).
用扫描仪对 杂交的 DNA芯片进行成像,获得每个探针区域的浓度数据作为基因表达数据(步骤P5)。
This naphthoquinone compound is located at such a position as facing to the cytosine to be determined when the photofunctional nucleic acid is hybridized with the DNA having the base sequence of the p53 gene.
这里,萘醌化合物设置在当光功能核酸与具有p53基因的碱基序列的DNA 杂交 时面对待测定的胞嘧啶的位置处。
Cyclopropane is analogous to a triangle and thus has bond angles of 60º, much lower than the preferred 109.5º of an sp3 hybridized carbon.
环丙烷类似于三角形,因此键角为 60°,远小于 sp3 化碳原子所需的 109.5°。
Even though they are often referred to as “nature documentaries,” these films are just as are hybridized and committed as Jarl’s grittier Mods series.
虽然它经常被称为自然纪录片,但它的 混合性 和参与度并不亚于 Jarl 大胆的 Mod 系列。
It is possible to efficiently obtain a fluorine-containing olefin in which the fluorine atoms bonded to the sp2 hybridized carbon atoms of a fluorine-containing olefin, such as TFE, have been substituted with organic groups by reacting a fluorine-containing olefin and an organic magnesium compound in the presence of a catalyst containing nickel or palladium.
在本发明中,通过使含氟烯烃与有机镁化合物在含有镍或钯的催化剂存在下反应,将与TFE等含氟烯烃的sp2 化碳原子键合的氟原子置换为可以有效地得到含氟烯烃。
The probe nucleic acids are fixed to the same positions as the primer immobilization regions or to probe immobilization regions in proximity thereto, and hybridized signals are independently detected.
将探针核酸固定在探针固定区域上与引物固定区域相同的位置或其附近,并独立地检测 杂交 信号。
The photofunctional nucleic acid is hybridized with the DNA having the base sequence of the p53 gene and then photo, the DNA is cleaved exclusively in the case where the cytosine facing to the naphthoquinone compound has been methylated.
通过 将该 光功能性核酸与具有p53基因的碱基序列的DNA杂交并用光照射,仅当面对萘醌化合物的胞嘧啶被甲基化时,该DNA才被切割。
At P = 1.4 GPa (f) the hybridized mode of transverse and longitudinal fluctuations (h-TL) does exist in addition to Nambu-Goldstone (NG) and Higgs-amplitude (L) modes.
在 P = 1.4 GPa 的压力诱导有序相 (f) 中,除了 Southern-Goldstone (NG) 模式和 Higgs (L) 模式外,还发现了纵向和横向波动的 混合 模式 (h-TL)存在、认识。
A target nucleic acid can be detected conveniently and with high sensitivity by using transglutaminase (TGase) and also by using a multilabeled nucleic acid probe having multiple labeling parts introduced therein covalently in advance or covalently introducing multiple labeling parts into a nucleic acid probe that has been hybridized with the target nucleic acid.
通过使用预先使用转谷氨酰胺酶(TGase)共价引入多个标记部分的多标记核酸探针,或者通过共价 标记 与目标核酸杂交的核酸探针。酸的检测很容易且灵敏度高。
Use is made of: (a) polynucleotide having a base sequence of SEQ ID No. 1, or (b) polynucleotide coding for a protein having D-lactic acid dehydrogenase activity, having been hybridized under stringent conditions with a probe prepared from the whole or part of a base sequence of SEQ ID No. 1 or complementary strand thereof.
(a)具有SEQ ID NO:1所示的核苷酸序列的多核苷酸;(b)与由SEQ ID NO:1所示的整个核苷酸序列或其一部分或其互补链制备的探针杂交的多核苷酸在 严格 条件下,并利用编码具有D-乳酸脱氢酶活性的蛋白质的多核苷酸。
This semiconductor element is characterized by comprising an electric current path (16) formed of a plurality of carbon nanotubes (18) and two or more electrodes (14, 15) connected to the electric current path, at least one or more of the electrodes being formed of a mixture of a metal with a carbon material (17) having an SP2 hybridized orbital such as a multiwall carbon nanotube, a glassy carbon, or graphite particles.
一种半导体装置,具有由多个碳纳米管(18)构成的电流路径(16),具有与该电流路径连接的两个以上的电极(14、15),并且具有至少一个电极。电极由金属和多壁碳纳米管、玻璃碳或石墨颗粒等具有SP2 杂化 轨道的碳材料(17)的混合物构成。
In the disordered phase at low pressures single mode of singlet – doublet excitation is observed.In contrast in the pressured induced ordered phase at 1.4 GPa, it was discovered that the hybridized mode of longitudinal and transverse fluctuations originated from noncollinearity of the magnetic structure as well as Nambu-Goldstone and Higgs-amplitude modes.
在低压自旋无序状态下,观察到单重态-双重态激发,而在1.4 GPa的有序相中,除了南部-戈德斯通模式和希格斯模式外,还观察到磁性结构的非磁性结构。结果表明,存在由共线性引起的纵向和横向 波动 的混合模式。
Jovial Foods sent me a box of their Organic Einkorn Wheat Berries to try.According to Jovial Foods, einkorn is “the world’s most ancient wheat and the only wheat that has never been hybridized .”
Yoki Foods 寄给我一盒他们的有机细菌浆果让我尝尝。Merry Foods 的细菌是唯一从未与世界上最古老的小麦 杂交 过的小麦。
A method of detecting a methylated cytosine of the invention comprises the steps of: hybridizing an oligonucleotide capable of hybridizing to a region containing a cytosine which is expected to be methylated in a sample DNA and having an abasic site at a position complementary to the cytosine to the sample DNA; oxidizing a methylated cytosine by reacting an oxidizing agent with the hybridized sample DNA formed in the previous step when a methylated cytosine is present therein; and detecting the oxidized methylated cytosine.
本发明的甲基化胞嘧啶的检测方法包括将与样品DNA中含有预期被甲基化的胞嘧啶的区域杂交并且在与胞嘧啶互补的位置处具有脱碱基位点的寡核苷酸与样品DNA组合。当存在甲基化胞嘧啶时,使该步骤中产生的 杂交 样品DNA与氧化剂反应,氧化甲基化胞嘧啶;该方法包括检测结合胞嘧啶的步骤。
The method for synthesizing a nucleic acid in which a complex of a target nucleic acid to which a primer oligonucleotide is hybridized and DNA polymerase β is formed, a fluorescently labeled dNTP is allowed to be incorporated into the DNA polymerase β, the fluorescently labeled dNTP is bound to the 3′ end of the primer oligonucleotide and the fluorescently labeled dNTP is allowed to be incorporated into the DNA polymerase β continuously, whereby a nucleic acid complementary to the target nucleic acid is extended from the 3′ end of the bound fluorescently labeled dNTP.
与引物寡核苷酸 杂交的 靶核酸与DNA聚合酶β之间形成复合物,荧光标记的dNTP掺入DNA聚合酶β中,并且荧光标记的dNTP与引物寡核苷酸的3’端结合。一种核酸合成方法,其中通过将荧光标记的dNTP连续地掺入DNA聚合酶β中,使与目标核酸互补的核酸从结合的荧光标记的dNTP的3’末端延伸。
The following are provided: a nucleic acid containing a base sequence represented by one of sequence numbers 1 to 1281; a nucleic acid at least 90% identical to the aforementioned nucleic acid; a nucleic acid hybridized with a complementary strand of the aforementioned nucleic acid under stringent conditions; a nucleic acid containing the second through eighth base sequences of a base sequence represented by one of sequence numbers 1 to 594; a cell or organ fibrosis control agent using a nucleic acid or the like comprising a base sequence that is complementary to the base sequence of an abovementioned nucleic acid; a diagnostic or therapeutic agent for disorders resulting from cell or organ fibrosis; an expression control agent for target genes of nucleic acids such as microRNAs; a control method or the like for cells and organs; and a method for screening for cell or organ fibrosis control agents.
本发明涉及包含SEQ ID NO:1至1281中任一个所表示的碱基序列的核酸、与该核酸具有90%以上同一性的核酸、以及在严格条件下与互补序列 杂交的 核酸。 、细胞或器官纤维化控制剂、细胞或器官纤维化引起的疾病的诊断或治疗剂、微小RNA等核酸靶基因的表达控制剂、细胞和器官控制方法等。提供了用于筛选纤维化控制剂的方法。
A method comprising: the double-stranded nucleic acid step wherein a nucleic acid probe immobilized on an electrode is hybridized with a gene sample to form a double-stranded nucleic acid; the step of adding an insertion agent comprising a compound having a double-stranded nucleic acid-binding site Ia, which is to be inserted specifically into the above-described double-stranded nucleic acid and forms a covalent bond with the double-stranded nucleic acid upon light irradiation, an electrochemically active site Fahaving an electrochemical activity, and a linking site La of linking the double-stranded nucleic acid-binding site Ia to the electrochemically active site Fa, and having substituent(s) comprising one or both of compounds represented by -Lb-Ib and -Lc-Fb at each of the sites as described above; the light irradiation step of forming a covalent bond between the double-stranded nucleic acid and the inserting agent; and the detection step of detecting the inserting agent forming a covalent bond with the double-stranded nucleic acid by an electrochemical measurement.
双链核酸步骤,其中固定在电极上的核酸探针与基因样品 杂交 以形成双链核酸;双链核酸结合位点Ia与双链形成共价键。添加由具有位点La的化合物组成的嵌入剂的步骤[0072] 在各位点具有由-Lb-Ib和-Lc-Fb表示的化合物中的一种或其组合构成的取代基。 光照射步骤,用于使双链核酸与嵌入剂共价键合;以及检测步骤,通过电化学测量来检测与双链核酸共价键合的嵌入剂。
Disclosed is an L-succinyl aminoacylase comprising (a) a protein coded by a gene consisting of the base sequence disclosed in sequence no. 1; (b) a protein consisting of the amino acid sequence disclosed in sequence no. 2; (c) a protein coded by a polynucleotide hybridized with a base sequence complementary to the base sequence disclosed in sequence no. 1 under stringent conditions, and which possesses L-succinyl aminoacylase activity; or (d) an amino acid sequence, in which one or multiple amino acids are substituted, deleted, inserted, and/or added to a protein consisting of the amino acid sequence disclosed in sequence no. 2, and which possesses L-succinyl aminoacylase activity.
根据本发明,(a)由由SEQ ID NO:1所示的核苷酸序列组成的基因编码的蛋白质;(b)由SEQ ID NO:2所示的氨基酸序列组成的蛋白质;( c)由由SEQ ID NO:1所示的核苷酸序列组成的基因编码的蛋白质;由在严格条件下与与该核苷酸序列互补的核苷酸序列 杂交 并具有L-琥珀酰氨基酰化酶活性的多核苷酸编码的蛋白质;或(d)由SEQ ID NO:2所示的氨基酸序列组成。 提供一种由其中一个或多个氨基酸被取代、缺失、插入和/或添加的氨基酸序列组成的L-琥珀酰酰基转移酶,且其具有L-琥珀酰氨基酰化酶活性。

听“ hybridized ”的陆地声音(发音)!

读法是【ˈhaɪ.brɪ.daɪzd】。 听下面的视频并大声发音【ˈhaɪ.brɪ.daɪzd】。

【必听】美国人解释“hybridized”的含义