简单汉语中“intron”的意思
名词
与
外显子
2
相比，外显子 2 是
一段 DNA，它中断了
生化
intron
基因，并且对蛋白质特异性没有贡献。
含义：[内含子]
intron是一个英语单词，有几个不同的含义。 让我们用例句来解释每个的含义和用法！
If the length of the
intron
exceeds this specification, it will not be mapped.
如果
内含子
长度超过此规格，则不会被映射。
Specify the maximum base length of the
intron
and exclude it from the mapping target when the adjacent exon distance is far away.
指定
内含子
的最大碱基长度，如果相邻的外显子相距较远，则不会进行映射。
When cDNA base sequence file is mapped on genome sequence, it distinguishes between exon and
intron
and registers it as a feature.
当 cDNA 碱基序列文件映射到基因组序列时，外显子和
内含子
被区分并注册为特征。
We show that cytochrome c oxidase subunit 7a related polypeptide (COX7RP) is a prototypic nuclear-encoded gene including perfect ERE within its
intron
1.
该基因与细胞色素c氧化酶复合物的亚基VIIa具有同源性，在核基因组中编码，并且在其
内含子
1中具有功能性雌激素反应元件。
ERAI gene consists of the XBP1 region containing an N-terminal domain and XBP1’s
intron
and the luciferase cDNA (Fig.B).
在 ERAI 基因中，含有 XBP1 蛋白和
内含子
的 cDNA 连接在荧光素酶编码序列的上游（右图 B）。
ひまわり – 広島大学シーズデータベース We found that mutations in the nuclear gene (At-nMat1a) responsible for the splicing of mitochondrial group II
intron
in plants led to the change in the accumulation of various useful materials.
向日葵 – 广岛大学种子数据库 研究内容 我们发现，具有剪接植物线粒体II组
内含子
功能的核基因组基因（At-nMat1a）的突变改变了积累的各种有用物质的量。
Type II diabetes is tested based on data obtained by analyzing a single nucleotide polymorphism at a base occurring in
intron
15 of KCNQ1 gene.
将分析KCNQ1基因
内含子
15中存在的单核苷酸多态性，并根据分析结果测试II型糖尿病。
Mechanisms by which these recurring structural variations have oncogenic effects have been identified for osteosarcoma (translocations confined to the first
intron
of TP53) and medulloblastoma (structural variants juxtapose GFI1 or GFI1B coding sequences proximal to active enhancer elements leading to transcriptional activation [enhancer hijacking]).
这些反复出现的结构变异产生癌症基因的机制包括骨肉瘤（仅限于 TP53 第一个
内含子
的易位）和髓母细胞瘤（一种结构变异，其中 GFI1 或 GFI1B 的编码序列是 已确定转录激活发生在紧密的位置）。与激活增强子元件并置（增强子劫持）。
[MEANS FOR SOLVING PROBLEMS] A splicing variant of c-myc gene transcriptional regulator FIR, a cDNA encoding the same or an mRNA corresponding to the same; a DNA containing a four-base repetitive sequence in
intron
2 of FIR gene; a method of detecting cancer by detecting the occurrence thereof; and an assay kit to be used therefor.
[解决方案] c-myc基因转录抑制因子FIR的剪接变体、编码它的cDNA、或相应的mRNA、在FIR基因的
内含子
2内含有4碱基重复序列的DNA，以及检测其存在的癌症检测。用于它的套件。
1: One family line with familiar myocardial disease comprising multiple arrhythmias antecedent to advanced atrioventricular block (FDCM-CD3B) Fig.: Results of Lamin A/C gene analysis of the proband of the FDCM-CD3 family line An IVS3-10A<G mutation was found in
intron
3 where a splicing error introduced 9 new bases and 3 new amino acids.
家族性心肌病先兆严重房室传导阻滞并并发各种心律失常的家系（FDCM-CD3B） 图 2. FDCM-CD3 家族先证者 Lamin A/C 基因分析结果 IVS3-10A 内含
子
3 <G 突变经鉴定并显示，由于剪接异常，插入了九个新碱基和三个新氨基酸。
A medicinal composition for treating cancer which contains, as the active ingredient, a nucleic acid, for example, a nucleic acid containing the sequence of the 3′-side half of
intron
3 of OncomiR-1/C13orf25 occurring in a human chromosome 13q31.3 or a part of the same, an antisense oligonucleotide against miRNA of miR-17-5p and/or miR20 occurring in the above-described chromosome or the like, wherein the above nucleic acid has an activity of inhibiting the proliferation of cancer, wherein miR-17-5p and/or miR20 are overexpressed, and inducing cell death thereof.
本发明提供了具有人染色体13q31.3中存在的OncomiR-1/C13orf25的
内含子
3的3’半部或其一部分、染色体中存在的miR-17-5p和/或miR20的序列的核酸含有核酸如针对miRNA的反义寡核苷酸作为活性成分，这些核酸具有抑制过表达miR-17-5p和/或miR20的癌症生长并诱导细胞增殖的活性。，涉及用于治疗癌症的药物组合物。
METHOD OF DETECTING CANCER USING SPLICING VARIANT OF c-myc GENE TRANSCRIPTIONAL REGULATOR FIR OR FOUR-BASE REPETITIVE SEQUENCE IN
INTRON
2
使用c-myc基因转录抑制因子FIR或内含
子
2内的4核苷酸重复序列的剪接变体的癌症检测方法
Mapping section: When mapping mRNA, cDNA, or amino acid sequence, specify the maximum base length to be regarded as an
intron
when the sequence is interrupted by
intron
.
映射部分：在映射 mRNA、cDNA 或氨基酸序列时，指定
当序列被内含子破坏时被视为内含子的
最大碱基长度
。
As polymorphisms relating to type 2 diabetes, polymorphisms in TFAP-2β gene (for example, substitution of guanine (G) at the 774-position in the first
intron
of the TFAP-2β gene into thymine (T), and a tandem repeat polymorphism in the first
intron
) are found out.
与2型糖尿病相关的多态性包括TFAP-2β基因中的多态性，例如在TFAP-2β
基因
的第一个
内含子
中的774位处鸟嘌呤（G）替换为胸腺嘧啶（T）；发现了串联重复多态性。
There are many more, even in
intron
2 alone.
在
《
2
》
中，他只出现在多个
结局
之一。
If searching for microsatellite markers in specific regions of a genome, for example within a particular
intron
, primers can be designed manually.
当检测位于基因组特定区域（例如某个基因的特定
外显子
）的微卫星时，可以直接设计引物。
In a typical case, this incorporation can be detected by PCR with the use of a primer specific to the
intron
3-containing region of the MLL4 gene and another primer specific to the X gene region of HBV.
一种突变芽孢杆菌属细菌，其在其基因组或质粒上具有通过将在sigA基因或与该基因对应的基因的上游的孢子形成阶段期间被特异性识别和转录的启动子
序列
连接而形成的DNA，以及突变芽孢杆菌属细菌。一种将编码外源蛋白质或多肽的基因导入细菌中的重组微生物，以及使用该重组微生物生产蛋白质或多肽的方法。
With this awareness, more than a decade ago Dr. Saido launched a project to develop a new mouse model that would allow more accurate evaluation of therapies for the disease.One of the major hurdles involved a part of the gene,
intron
16, which they discovered was necessary for creating more specific models.The first mice model they developed (NL-F/NL-F) was knocked in with two mutations found in human familial Alzheimer’s disease.
结果
显示，淀粉样斑块比同龄二代APP小鼠更早形成，神经炎症加速、记忆学习能力更早恶化，导致病理恶化。这样，通过分析第二代APP小鼠和其他转基因小鼠的杂交后代，将有可能发现加剧或改善淀粉样斑块的因素。此外，研究小组成功培育出第三代APP小鼠，该小鼠将Arctic突变（一种增加Aβ积累的家族性阿尔茨海默病突变）融入到第二代APP小鼠中。
Intron
figure selection button: Select the display method when displaying features with introns in the feature lane of the main feature map.
内含子
图选择按钮：选择在主特征图的特征泳道中显示带有内含子的特征时的显示方式。
Thus, it is found that an enhancer for a promoter, which comprises an
intron
sequence for a major immediate early gene (MIE) of human herpes virus-6 (HHV-6) (particularly HHV-6B) or a fragment of the
intron
sequence, has a potent promoter activity.
即，发现含有人疱疹病毒6型(HHV-6)(特别是HHV-6B)的主要立即早期基因(MIE)的
内含子
序列或其片段的启动子增强子具有强
的
启动子活性。解决了。
听“ intron ”的土声（发音）！
读法是【ˈɪntrɒn】。 听下面的视频并大声发音【ˈɪntrɒn】。